IRX4 Antibody, FITC conjugated

Datasheet

Code	CSB-PA011836LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) IRX4 Polyclonal antibody

Uniprot No.

P78413

Target Names

IRX4

Alternative Names

Homeodomain protein IRXA3 antibody; Iroquois homeobox protein 4 antibody; Iroquois-class homeodomain protein IRX-4 antibody; Iroquoisclass homeodomain protein IRX4 antibody; Irx4 antibody; IRX4_HUMAN antibody; IRXA3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Iroquois-class homeodomain protein IRX-4 protein (287-363AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Likely to be an important mediator of ventricular differentiation during cardiac development.

Gene References into Functions

We independently validated IRX4 as a potential prostate cancer risk gene through cis-expression quantitative trait loci analysis of prostate cancer risk variants. PMID: 24022300
the prostate cancer (PC)-susceptibility locus represented by rs12653946 at 5p15 is likely to regulate IRX4 expression in prostate which could suppress PC growth by interacting with the VDR pathway, conferring to PC susceptibility PMID: 22323358
IRX4 had a potential causative impact on the development of congenital heart disease, particularly ventricular septal defect. PMID: 21544582
Among migraineurs with aura rs7698623 in MEPE (OR = 6.37; 95% CI 3.15-12.90; p = 2.7x10(-7)) and rs4975709 in IRX4 (OR = 5.06; 95% CI 2.66-9.62; p = 7.7x10(-7)) appeared to be associated with ischemic stroke. PMID: 21779381
Polymorphism A381>G of the Irx4 gene may have a modifier effect on septal thickness, resulting in increased corrected QT dispersion and higher outflow gradients. PMID: 18497553

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Subcellular Location

Nucleus.

Protein Families

TALE/IRO homeobox family

Tissue Specificity

Predominantly expressed in cardiac ventricles.

Database Links

HGNC: 6129

OMIM: 606199

KEGG: hsa:50805

STRING: 9606.ENSP00000231357

UniGene: Hs.196927

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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